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Imipenem Cilastatin Injection

Name: Imipenem Cilastatin Injection
Brand: Luckys Pharma Lab Pvt Ltd
Price: 1059.0 INR
Availability: InStock

Price 1059.0 INR/ Unit

Get a Price/Quote

MOQ : 100 Units

Imipenem Cilastatin Injection Specification

Dosage Form
As directed by physician

Indication
As directed by physician

Salt Composition
Imipenem 500mg + Cilastatin 500mg

Pacakaging (Quantity Per Box)
1 Vial in box

Drug Type
Injection

Ingredients
imipenem cilastatin injection

Physical Form
Powder

Function
Anti-Bacterial

Recommended For
as prescribed by the physician

Dosage
as prescribed by the physician

Dosage Guidelines
as prescribed by physician

Suitable For
Adults

Quantity
1 Unit

Storage Instructions
Cool, dry and dark place

Imipenem Cilastatin Injection Trade Information

Minimum Order Quantity
100 Units

FOB Port
Cargo, Logistic, Courier

Payment Terms
Cash Advance (CA), Cash in Advance (CID), Cash on Delivery (COD)

Supply Ability
100000 Units Per Month

Delivery Time
1 Days

Sample Available
No

Sample Policy
Free samples available with shipping and taxes paid by the buyer

Packaging Details
1 Vial in a pack

Main Export Market(s)
Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Main Domestic Market
All India

Certifications
WHO-GMP Certified

About Imipenem Cilastatin Injection

Product Name: CILAST
Composition:
Each vial contains:

Imipenem USP 500 mg
Cilastatin USP 500 mg
Dosage Form: Sterile powder for injection (to be reconstituted)

Description:

CILAST is a broad-spectrum -lactam antibiotic injection containing Imipenem, a potent carbapenem antibiotic, and Cilastatin, a renal dehydropeptidase inhibitor. Cilastatin prevents the renal metabolism of Imipenem, ensuring effective therapeutic levels and enhancing its antibacterial activity.

Indications:

CILAST is indicated for the treatment of a wide variety of serious bacterial infections, including:

Lower respiratory tract infections
Intra-abdominal infections
Urinary tract infections
Gynecological infections
Skin and soft tissue infections
Bone and joint infections
Septicemia
Endocarditis (caused by susceptible organisms)

Mechanism of Action:

Imipenem acts by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs), leading to cell death.
Cilastatin inhibits the renal enzyme dehydropeptidase-I, preventing Imipenem degradation in the kidneys and extending its antibacterial activity.

Key Features:

Ultra-broad spectrum active against Gram-positive, Gram-negative, and anaerobic bacteria
Enhanced efficacy with Cilastatin co-administration
Used in hospital-acquired and drug-resistant infections
Well tolerated with a proven safety profile in severe infections

Dosage & Administration:

Adults: 250 mg to 1 g every 6 to 8 hours IV, depending on the severity of infection
Maximum dose: Not to exceed 4 g/day of Imipenem
Route: Intravenous infusion over 3060 minutes
Reconstitution and dilution instructions should be followed as per the prescribing information.

Always use under the supervision of a registered medical practitioner.

Packaging:

Vial with dry powder
Supplied with sterile water or as per standard hospital dilution protocols

Storage:

Store below 25C. Protect from light and moisture.
After reconstitution, use the solution immediately or within the specified time (usually 4 hours at room temperature or 24 hours if refrigerated).

Comprehensive Antibacterial Therapy

Imipenem Cilastatin Injection offers robust action against a wide range of bacterial pathogens. Ideal for serious or complicated infections, it is recommended when alternative antibiotics fail, ensuring effective and reliable clinical outcomes for adult patients under physician supervision.

Formulation and Packaging Details

This medication is provided as a dry powder injectable in a single vial per box, simplifying dosing for healthcare professionals. Each vial contains a combination of Imipenem 500mg and Cilastatin 500mg for dual-action efficacy.

Proper Usage and Administration

Imipenem Cilastatin Injection should only be administered by a healthcare professional via injection as prescribed by a physician. Dosage and frequency depend on the specific infection and patient factors, ensuring safety and optimal antibacterial effect.

FAQ's of Imipenem Cilastatin Injection:

Q: How is Imipenem Cilastatin Injection prepared and administered?

A: Imipenem Cilastatin Injection comes in dry powder form and must be reconstituted with a suitable diluent by a healthcare professional. Once mixed, it is given as an injection, strictly as prescribed by a physician.

Q: What are the main benefits of using Imipenem Cilastatin Injection?

A: This antibiotic combination is highly effective against many resistant bacterial infections, offering rapid and broad-spectrum antibacterial action when conventional antibiotics may not work.

Q: When should Imipenem Cilastatin Injection be used?

A: It should be used in adults with severe or complicated bacterial infections, as recommended and directed by a physician. It is not intended for minor infections or self-medication.

Q: Where should the injection be stored before use?

A: The vial should be kept in a cool, dry, and dark place to maintain stability and effectiveness until needed for administration.

Q: What is the process for dosage and administration of this medication?

A: Dosage and administration depend on the type and severity of infection, typically determined by the physician. Never adjust the dosage without professional guidance.

Q: Who can use Imipenem Cilastatin Injection?

A: This product is suitable for adults and must be prescribed by a qualified healthcare provider. Always follow the physician's instructions for safe use.

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